Boosting Monoclonal Antibody Yields with Peptones: Evidence-Based Strategies for CHO Cell Success
Synopsis
Explore how biologically-derived peptones are transforming monoclonal antibody (mAb) production in CHO cell cultures. This in-depth whitepaper by Thermo Fisher Scientific presents real-world data, optimization methods, and product quality outcomes to help biomanufacturers maximize titer, maintain cell viability, and ensure process consistency.
Key Highlights
Up to 64.5% Titer Improvement: Learn how specific peptone combinations like cotton and wheat significantly enhance mAb yields across multiple CHO cell lines
Product Quality Maintained: Charge variant and glycan profile analyses confirm stable protein quality despite peptone supplementation.
Consistent Performance Across Batches: Demonstrated lot-to-lot consistency of Gibco™ peptones ensures reproducibility for scalable bioprocessing.
Optimized for Animal-Origin Free (AOF) Use: Supports regulatory compliance with AOF peptone options without compromising performance.
