Karikó and Weissman Win Nobel for COVID-19 mRNA Vaccine Work in 2023

04 October 2023 | Wednesday | News

The 2023 Nobel Prize in Physiology or Medicine has been jointly awarded to Katalin Karikó and Drew Weissman by the Nobel Assembly at Karolinska Institutet. They have been recognized for their pioneering research in nucleoside base modifications that played a pivotal role in the creation of highly effective mRNA vaccines against COVID-19.

These groundbreaking discoveries by both laureates were instrumental in the rapid development of mRNA vaccines during the early 2020 pandemic, revolutionizing our comprehension of how mRNA interacts with the immune system. Their contributions significantly accelerated vaccine development, addressing one of the most profound global health challenges of our era.

Dr. Katalin Karikó, a Hungarian-American biochemist, specializes in ribonucleic acid-mediated mechanisms, particularly in vitro-transcribed messenger RNA for protein replacement therapy.

Dr. Drew Weissman, an American physician-scientist, is renowned for his contributions to RNA biology, which paved the way for the development of mRNA vaccines, notably those produced by BioNTech/Pfizer and Moderna. Dr. Weissman's laboratory in the United States focuses on RNA and innate immune system biology, applying these insights to advance vaccine research and gene therapy.


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