Singleron Introduces AccuraSCOPE® Single Cell Transcriptome Platform

31 January 2024 | Wednesday | News

Singleron Biotechnologies, a leader in single cell multi-omic solutions for precision medicine, announced two new commercial product launches : AccuraSCOPE® Single Cell Transcriptome and Genome Library Kit and the AccuraSCOPE® Single Cell Full-Length Transcriptome Library Kit.
Image Source : Public Domain

Image Source : Public Domain

AccuraSCOPE  Single Cell Transcriptome and Genome Library Kit opens new possibilities for single cell multi-omic analysis by profiling the entire genome and transcriptome simultaneously. In addition to single cell RNA sequencing, this method enables deep single cell genome sequencing, amplifying ultra-low quantities of DNA from individual cells. This facilitates the comprehensive detection of single nucleotide variants and chromosomal aberrations at single cell level. Using proprietary bead-based technology, it captures both genomic DNA and mRNA from each cell and converts them to high-quality sequencing libraries. The integrated analysis of a cell's transcriptome and genome provides a comprehensive understanding of cellular heterogeneity in normal development and disease. The kit's multiplex design and streamlined workflow allow for single-cell mRNA and DNA library preparation from up to 384 single cells in parallel in a single day, significantly reducing time and costs.

Another new product in the AccuraSCOPE portfolio, AccuraSCOPE Single Cell Full-Length Transcriptome Library Kit, adds full-length, comprehensive, and rapid RNA sequencing library preparation to the toolkit. It enables the detection of alternative splicing at the single cell level, substantially reducing hands-on time compared to existing full-length single cell RNAseq methods.

The latest innovations were developed to particularly aid clinical researchers in oncology, gene, and cell therapy, as well as immunology and reproductive biology. Accurate detection of genomic and transcriptomic changes can unveil the relationship between genomic dynamics and gene expression profiles as well as uncover the functional impact of point mutations and copy number variations.

To meet customers' data analysis needs when using the new AccuraSCOPE products, Singleron has developed two bioinformatic analysis pipelines. The RNA sequencing data analysis pipeline covers the analysis workflow from FASTQ files to count matrix, while the DNA data analysis pipeline starts with FASTQ files and includes variance calling and variant annotation.


Stay Connected

Sign up to our free newsletter and get the latest news sent direct to your inbox


Forgot your password?



Lost your password? Please enter your email address. You will receive a link to create a new password.

Back to log-in