Pillar Biosciences, Inc. ("Pillar"), LC-SCRUM-Asia and LSI Medience Corporation ("LSI Medience")  announced a collaboration to support genomic screening of blood-based samples from patients with lung cancer as part of the LC-SCRUM-Asia project in Japan.

Following approval of a revision to the LC-SCRUM-Asia project protocol, the participating organizations plan to begin testing in August 2026. The project is expected to include approximately 2,000 patients over a two-year period.

Pillar's oncoReveal® Essential+ assay has been validated at LSI Medience for use as a screening test for circulating cell-free DNA (cfDNA) and cell-free RNA (cfRNA) samples collected from patients with lung cancer participating in the LC-SCRUM-Asia project. Testing will be performed by LSI Medience to support identification of genomic alterations relevant to the project's research objectives.

"LC-SCRUM-Asia has established an important collaborative framework for advancing precision oncology research in lung cancer," said Daniel Harma, Chief Commercial Officer, Pillar Biosciences. "We are pleased that oncoReveal Essential+ has been validated at LSI Medience for screening both cfDNA and cfRNA samples and look forward to supporting this large-scale project in Japan."

"Rapid and reliable genomic testing is essential for identifying patients who may benefit from biomarker-driven clinical studies and emerging precision therapies," said Dr. Koichi Goto of LC-SCRUM-Asia. "The use of oncoReveal® Essential+ through LSI Medience will provide the LC-SCRUM-Asia network with a highly accurate and accessible liquid biopsy solution for analyzing cfDNA and cfRNA from patients with non-small cell lung cancer, while supporting the rapid turnaround needed for clinical research."

Supporting blood-based genomic screening in lung cancer
Liquid biopsy testing can enable genomic analysis from blood samples when tissue is limited or when a minimally invasive sampling approach is desirable. By combining analysis of cfDNA and cfRNA, the LC-SCRUM-Asia project is designed to support broad screening for genomic alterations in patients with lung cancer.

The planned use of oncoReveal Essential+ within the LC-SCRUM-Asia project reflects the assay's ability to support targeted NGS analysis from blood-based specimens within a decentralized laboratory workflow.